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تسجيل

Analysis of MDMA

المؤلف:  Sue Jickells , Adam Negrusz (Editors)

المصدر:  Clarkes Analytical Forensic Toxicology

الجزء والصفحة:  75

2026-09-20

20

Analysis of MDMA

Colour test.

The Marquis test gives a blue–black colour with MDMA.

Qualitative analysis.

Base extraction into an organic solvent and/or derivatisation prior to GC-MS analysis is common in the separation and identification of MDMA, although GC analysis can also be carried out without derivatisation.

Quantitative analysis, profiling and/or comparison of MDMA

To perform a quantitative analysis on ‘ecstasy’ tablets, these must first be ground to produce a homogeneous powder and the MDMA content determined by either GC (either directly or base extracted) or HPLC. Chemical profiling of tablets that contain MDMA involves the examination and/or quantification of the drug and the main adulterants present, such as caffeine, sugars and binding agents. In addition to the main ingredients, many trace-level impurities from the synthetic process may be present and can be used for comparison (Bohn et al. 1993; Renton et al. 1993). As already mentioned in this chapter, tablet comparisons can also be made using (so-called) ballistic analysis. This uses general physical features and microscopic examination of defects and punch marks for comparison. The difficulty is that a large fraction of illicit tablets  in circulation may be almost identical at any one time.