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D-Lysergic Acid Diethyl Amide

المؤلف:  Max M. Houck، Jay A. Siegel

المصدر:  Fundamentals of Forensic Science

الجزء والصفحة:  p335-336

2026-08-08

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D-Lysergic Acid Diethyl Amide

LSD is not a naturally occurring substance but is derived from ergot alkaloids which themselves are derived from a grain fungus. This mold, if incorporated into bread products made from infected grain, can result in a disorder called ergotism or St Anthony’s Fire . LSD is the most potent and certainly the most famous of the hallucinogens and the one that is most responsible for popularizing this genre of drugs. As little as 50 µg (a droplet smaller than a period on this page) of LSD can cause auditory and visual hallucinogens that can last up to 12 h. LSD is not addictive and psychological dependence has been rarely recorded, but it can cause psycho sis in borderline cases and often gives rise to flashbacks, episodes of hallucinations months or years after a dose of the drug was taken. It has also been implicated in liver damage among regular users. LSD is normally taken in unusual dosage forms. It is a colorless, odorless, tasteless liquid. It may be dissolved in a volatile solvent and then impregnated onto absorbent paper, which is often decorated with colorful cartoon characters. Once dried, the paper is cut up into small squares and ingested. This form is called “blotter acid.” This is shown in Figure 1. Other forms of LSD include tiny colorful tablets (microdots) or small pieces of impregnated, dried gelatin (window panes). There have been cases where a dose of LSD was put behind a post age stamp on a letter and mailed to another user.

FIGURE 1 Blotter acid. D-Lysergic acid diethyl amide (LSD) is dissolved in a solvent and poured onto absorbent paper. The solvent is allowed to evaporate, leaving the LSD. The paper is cut into small squares and eaten.