Mid- Late Follicular Phase
المؤلف:
Wass, J. A. H., Arlt, W., & Semple, R. K. (Eds.).
المصدر:
Oxford Textbook of Endocrinology and Diabetes
الجزء والصفحة:
3rd edition , p1262
2026-10-26
135
During mid- late follicular period, namely preovulatory phase, dominant follicle grows up with a rate of 1– 4 mm per day and reaches to the maximal diameter of 30 mm. There is a steady increase in the aromatase activity and hence oestradiol levels but a contradictory decrease in fluidic AMH concentration. IGF- II continues to induce aromatase activity and oocyte- derived substances. GDF- 9 and BMP- 15 are involved in the process of follicle development and cumulus expansion. There are also increased numbers of LH receptors, which will be used during ovulation, and time of triggering.
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