Hydrolysing nitriles: how to make the almond extract, mandelic acid
المؤلف:
Jonathan Clayden , Nick Greeves , Stuart Warren
المصدر:
ORGANIC CHEMISTRY
الجزء والصفحة:
ص213-214
2025-05-12
425
Closely related to the amides are nitriles. You can view them as primary amides that have lost one molecule of water and, indeed, they can be made by dehydrating primary amides.
They can be hydrolysed just like amides too. Addition of water to the protonated nitrile gives a primary amide, and hydrolysis of this amide gives carboxylic acid plus ammonia.
You met a way of making nitriles—from HCN (or NaCN + HCl) plus aldehydes—in Chapter 6: the hydroxy nitrile products are known as cyanohydrins. With this in mind, you should be able to suggest a way of making mandelic acid, an extract of almonds, from benzaldehyde.
الاكثر قراءة في مواضيع عامة في الكيمياء العضوية
اخر الاخبار
اخبار العتبة العباسية المقدسة
