Reaction of organometallic reagents with carbon dioxide: Synthesis of carboxylic acids
المؤلف:
University of Missouri System
المصدر:
Organic Chemistry ii
الجزء والصفحة:
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9-10-2020
1919
Reaction of organometallic reagents with carbon dioxide: Synthesis of carboxylic acids
Grignard reagents can be also be carboxylated simply by pouring the organic solution over dry ice (solid CO2), then adding aqueous HCl:
Or in general: